Cargando…

In silico studies of Potency and safety assessment of selected trial drugs for the treatment of COVID-19

SARS-CoV-2 has caused millions of infections and hundreds of thousands of deaths globally. Presently, no cure for SARS-CoV-2 infection is available; thus, all hands are on deck for new drug discovery. Although, several studies have reported the potentials of some already approved drugs for the treat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adegbola, Peter Ifeoluwa, Fadahunsi, Olumide Samuel, Adegbola, Aanuoluwa Eunice, Semire, Banjo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295030/ https://www.ncbi.nlm.nih.gov/pubmed/34312587 http://dx.doi.org/10.1007/s40203-021-00105-x

Ejemplares similares

Molecular docking and ADMET studies of Allium cepa, Azadirachta indica and Xylopia aethiopica isolates as potential anti-viral drugs for Covid-19
por: Adegbola, Peter Ifeoluwa, et al.
Publicado: (2021)

Computational prediction of nimbanal as potential antagonist of respiratory syndrome coronavirus
por: Adegbola, Aanuoluwa Eunice, et al.
Publicado: (2021)

Potential inhibitory properties of structurally modified quercetin/isohamnetin glucosides against SARS-CoV-2 Mpro; molecular docking and dynamics simulation strategies
por: Adegbola, Peter Ifeoluwa, et al.
Publicado: (2023)

The Role of Poly-Herbal Extract in Sodium Chloride-Induced Oxidative Stress and Hyperlipidemia in Male Wistar Rats
por: Olorunnisola, Olubukola Sinbad, et al.
Publicado: (2021)

A Review on Ethno-Medicinal and Pharmacological Activities of Sphenocentrum jollyanum Pierre
por: Olorunnisola, Olubukola Sinbad, et al.
Publicado: (2017)

Phyllanthus amarus attenuated derangement in renal-cardiac function, redox status, lipid profile and reduced TNF-α, interleukins-2, 6 and 8 in high salt diet fed rats
por: Olorunnisola, Olubukola Sinbad, et al.
Publicado: (2021)

Phytochemistry, nutritional composition, and pharmacological activities of Thaumatococcus daniellii (Benth): a review
por: Fadahunsi, Olumide, et al.
Publicado: (2021)

Health risk assessment and heavy metal accumulation in fish species (Clarias gariepinus and Sarotherodon melanotheron) from industrially polluted Ogun and Eleyele Rivers, Nigeria
por: Adegbola, Ifeoluwa Peter, et al.
Publicado: (2021)

Emerging Data on Fistula Laser Closure (FiLaC) for the Treatment of Perianal Fistulas; Patient Selection and Outcomes
por: Adegbola, Samuel O, et al.
Publicado: (2021)

Dataset on in-silico investigation on triazole derivatives via molecular modelling approach: A potential glioblastoma inhibitors
por: Oyebamiji, Abel Kolawole, et al.
Publicado: (2020)

Dataset on the DFT-QSAR, and docking approaches for anticancer activities of 1, 2, 3-triazole-pyrimidine derivatives against human esophageal carcinoma (EC-109)
por: Adegoke, Rhoda Oyeladun, et al.
Publicado: (2020)

Theoretical calculations of molecular descriptors for anticancer activities of 1, 2, 3-triazole-pyrimidine derivatives against gastric cancer cell line (MGC-803): DFT, QSAR and docking approaches
por: Oyewole, Rhoda Oyeladun, et al.
Publicado: (2020)

Dataset on Insilico approaches for 3,4-dihydropyrimidin-2(1H)-one urea derivatives as efficient Staphylococcus aureus inhibitor
por: Oyebamiji, Abel Kolawole, et al.
Publicado: (2020)

Anti-gastric cancer activity of 1,2,3-triazolo[4,5-d]pyrimidine hybrids (1,2,3-TPH): QSAR and molecular docking approaches
por: Kolawole, Oyebamiji Abel, et al.
Publicado: (2020)

Electronic and optical properties’ tuning of phenoxazine-based D-A(2)-π-A(1) organic dyes for dye-sensitized solar cells. DFT/TDDFT investigations
por: Afolabi, Samson Olusegun, et al.
Publicado: (2021)

Genomics and Pain Research in Sickle Cell Disease: An Explanation of Heterogeneity?
por: Adegbola, Maxine
Publicado: (2011)

Describing the Stem Cell Potency: The Various Methods of Functional Assessment and In silico Diagnostics
por: Singh, Vimal K., et al.
Publicado: (2016)

Assessment of peri‐urban livestock producers’ willingness to pay for improved forages as cash crops
por: Ouédraogo, Adama, et al.
Publicado: (2022)

Dataset on insightful bio-evaluation of 2-(quinoline-4-yloxy)acetamide analogues as potential anti-Mycobacterium tuberculosis catalase-peroxidase agents via in silico mechanisms
por: Oyebamiji, Abel Kolawole, et al.
Publicado: (2021)

The incidence, risk factors and determinants of perinatal outcome of umbilical cord prolapses in Lagos, Nigeria
por: Adegbola, Omololu, et al.
Publicado: (2017)

Funding for Postbariatric Body-Contouring (Bariplastic) Surgery in England: A Postcode Lottery
por: Mukherjee, Samrat, et al.
Publicado: (2014)

Molecular properties and In silico bioactivity evaluation of (4-fluorophenyl)[5)-3-phen-(4-nitrophenyl yl-4,5-dihydro-1H-pyrazol-1-yl]methanone derivatives: DFT and molecular docking approaches
por: Omotayo, Ibrahim A., et al.
Publicado: (2023)

Intra-abdominal removal of a displaced hip prosthesis
por: Morrison, Rory, et al.
Publicado: (2014)

Editorial: New epidemiological, etiological and management insights into community-acquired pneumonia in children: subregional, regional and global perspectives
por: Falade, Adegoke G., et al.
Publicado: (2023)

How to Select the Proper Potency
Publicado: (1890)

Inhibition of In Vivo Growth of Plasmodium berghei by Launaea taraxacifolia and Amaranthus viridis in Mice
por: Adetutu, Adewale, et al.
Publicado: (2016)

Anti-TNF Therapy in Crohn’s Disease
por: Adegbola, Samuel O., et al.
Publicado: (2018)

Dataset on biochemical inhibiting activities of selected phytochemicals in Azadirachta indica L as potential NS2B–NS3 proteases inhibitors
por: Oyebamiji, Abel Kolawole, et al.
Publicado: (2023)

Antidoting Crude Drugs with Potencies
por: Holcombe, A. W.
Publicado: (1894)

THE MICROBIOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN A RESOURCE - LIMITED SETTING: IS ACID-FAST BACILLI MICROSCOPY ALONE SUFFICIENT?
por: Odubanjo, M.O., et al.
Publicado: (2011)

Anticancer metallohelices: nanomolar potency and high selectivity
por: Kaner, Rebecca A., et al.
Publicado: (2016)

Assessment of self-reported adherence among patients with type 2 diabetes in Matlala District Hospital, Limpopo Province
por: Adegbola, Sadeen A., et al.
Publicado: (2016)

Heterogeneity in outcome selection, definition and measurement in studies assessing the treatment of cryptoglandular anal fistula: findings from a systematic review
por: Machielsen, A. J. H. M., et al.
Publicado: (2021)

Evaluation of the Comparative Efficacy and Safety of Artemether-Lumefantrine, Artesunate-Amodiaquine and Artesunate-Amodiaquine-Chlorpheniramine (Artemoclo™) for the Treatment of Acute Uncomplicated Malaria in Nigerian Children
por: Falade, C.O., et al.
Publicado: (2014)

Drug Screening in Human Cells by NMR Spectroscopy Allows the Early Assessment of Drug Potency
por: Luchinat, Enrico, et al.
Publicado: (2020)

Livestock feed resources in the West African Sahel
por: Amole, Tunde, et al.
Publicado: (2021)

Susceptibility of Selected Multi-Drug Resistant Clinical Isolates to Leaves of Carpolobia lutea
por: Anibijuwon, Ibikunle, et al.
Publicado: (2018)

Medical and surgical management of perianal Crohn’s disease
por: Adegbola, Samuel O., et al.
Publicado: (2018)

Safety assessment of drug combinations used in COVID-19 treatment: in silico toxicogenomic data-mining approach
por: Baralić, Katarina, et al.
Publicado: (2020)

Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design
por: Holt, Graham T., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f8uo8ohk0s4v49rcnlu231eh3h