Cargando…
A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial
BACKGROUND: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. AIM: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. DESIGN: A bloc...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295113/ https://www.ncbi.nlm.nih.gov/pubmed/33586003 http://dx.doi.org/10.1007/s00520-021-06021-2 |
_version_ | 1783725374499192832 |
---|---|
author | Monsen, Ragnhild Elisabeth Herlofson, Bente Brokstad Gay, Caryl Fjeld, Katrine Gahre Hove, Lene Hystad Malterud, Karl Egil Saghaug, Elisabeth Slaaen, Joran Sundal, Tone Tollisen, Anita Lerdal, Anners |
author_facet | Monsen, Ragnhild Elisabeth Herlofson, Bente Brokstad Gay, Caryl Fjeld, Katrine Gahre Hove, Lene Hystad Malterud, Karl Egil Saghaug, Elisabeth Slaaen, Joran Sundal, Tone Tollisen, Anita Lerdal, Anners |
author_sort | Monsen, Ragnhild Elisabeth |
collection | PubMed |
description | BACKGROUND: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. AIM: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. DESIGN: A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO (n=44) or NS (n=44). Numerical rating scales (NRS, 0–10) and 12 items from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Oral Health 17 (EORTC QLQ-OH17) measured patient-reported oral symptoms. An oral examination was performed before and after the intervention. SETTING/PARTICIPANTS: This study included adult patients with late-stage cancer in an inpatient hospice unit. RESULTS: Of the 88 patients included (mean age=63.9 years, SD=10.6), 73 (83%) completed the study. At baseline, 78% reported dry mouth on the EORTC QLQ-OH17, and 80% rated dry mouth ≥4 on the NRS. Total oral health scores based on the 12 EORTC QLQ-OH17 items improved similarly in both groups (p<0.001). However, dry mouth ratings on both the EORTC QLQ-OH17 (p=0.036) and NRS (p=0.045) improved more in the SO group than in the NS group. Plaque on the teeth improved in both the SO (p=0.008) and NS (p=0.018) groups, but plaque on the tongue and erythema only improved with NS. CONCLUSIONS: This study did not detect an overall significant difference between SO and NS. Both mouth rinses improved oral health parameters, indicating that systematic assessment and oral care may reduce oral discomfort. TRIAL REGISTRATION: NCT02067572 |
format | Online Article Text |
id | pubmed-8295113 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-82951132021-07-23 A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial Monsen, Ragnhild Elisabeth Herlofson, Bente Brokstad Gay, Caryl Fjeld, Katrine Gahre Hove, Lene Hystad Malterud, Karl Egil Saghaug, Elisabeth Slaaen, Joran Sundal, Tone Tollisen, Anita Lerdal, Anners Support Care Cancer Original Article BACKGROUND: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. AIM: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. DESIGN: A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO (n=44) or NS (n=44). Numerical rating scales (NRS, 0–10) and 12 items from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Oral Health 17 (EORTC QLQ-OH17) measured patient-reported oral symptoms. An oral examination was performed before and after the intervention. SETTING/PARTICIPANTS: This study included adult patients with late-stage cancer in an inpatient hospice unit. RESULTS: Of the 88 patients included (mean age=63.9 years, SD=10.6), 73 (83%) completed the study. At baseline, 78% reported dry mouth on the EORTC QLQ-OH17, and 80% rated dry mouth ≥4 on the NRS. Total oral health scores based on the 12 EORTC QLQ-OH17 items improved similarly in both groups (p<0.001). However, dry mouth ratings on both the EORTC QLQ-OH17 (p=0.036) and NRS (p=0.045) improved more in the SO group than in the NS group. Plaque on the teeth improved in both the SO (p=0.008) and NS (p=0.018) groups, but plaque on the tongue and erythema only improved with NS. CONCLUSIONS: This study did not detect an overall significant difference between SO and NS. Both mouth rinses improved oral health parameters, indicating that systematic assessment and oral care may reduce oral discomfort. TRIAL REGISTRATION: NCT02067572 Springer Berlin Heidelberg 2021-02-14 2021 /pmc/articles/PMC8295113/ /pubmed/33586003 http://dx.doi.org/10.1007/s00520-021-06021-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Monsen, Ragnhild Elisabeth Herlofson, Bente Brokstad Gay, Caryl Fjeld, Katrine Gahre Hove, Lene Hystad Malterud, Karl Egil Saghaug, Elisabeth Slaaen, Joran Sundal, Tone Tollisen, Anita Lerdal, Anners A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial |
title | A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial |
title_full | A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial |
title_fullStr | A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial |
title_full_unstemmed | A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial |
title_short | A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial |
title_sort | mouth rinse based on a tea solution of salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295113/ https://www.ncbi.nlm.nih.gov/pubmed/33586003 http://dx.doi.org/10.1007/s00520-021-06021-2 |
work_keys_str_mv | AT monsenragnhildelisabeth amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT herlofsonbentebrokstad amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT gaycaryl amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT fjeldkatrinegahre amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT hovelenehystad amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT malterudkarlegil amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT saghaugelisabeth amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT slaaenjoran amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT sundaltone amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT tollisenanita amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT lerdalanners amouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT monsenragnhildelisabeth mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT herlofsonbentebrokstad mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT gaycaryl mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT fjeldkatrinegahre mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT hovelenehystad mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT malterudkarlegil mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT saghaugelisabeth mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT slaaenjoran mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT sundaltone mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT tollisenanita mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial AT lerdalanners mouthrinsebasedonateasolutionofsalviaofficinalisfororaldiscomfortinpalliativecancercarearandomizedcontrolledtrial |