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Depressive symptoms and 5-year incident metabolic syndrome among older adults

Little is known regarding the association between depressive symptoms and metabolic syndrome (MetS) among older Chinese adults. This study aimed to examine the association of depressive symptoms with MetS and its components among Chinese elderly. Based on whether they showed depressive symptoms at b...

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Autores principales: Wu, Qian, Hua, Yi-Ying, Ma, Qing-Hua, Xu, Yong, Chen, Xing, Pan, Chen-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295297/
https://www.ncbi.nlm.nih.gov/pubmed/34290362
http://dx.doi.org/10.1038/s41598-021-94503-y
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author Wu, Qian
Hua, Yi-Ying
Ma, Qing-Hua
Xu, Yong
Chen, Xing
Pan, Chen-Wei
author_facet Wu, Qian
Hua, Yi-Ying
Ma, Qing-Hua
Xu, Yong
Chen, Xing
Pan, Chen-Wei
author_sort Wu, Qian
collection PubMed
description Little is known regarding the association between depressive symptoms and metabolic syndrome (MetS) among older Chinese adults. This study aimed to examine the association of depressive symptoms with MetS and its components among Chinese elderly. Based on whether they showed depressive symptoms at baseline, 262 age-gender-matched participants from a community-based cohort study were included. The presence of depressive symptoms was measured using the nine-item Patient Health Questionnaire (PHQ-9). MetS was defined according to the Adult Treatment Panel III of the National Cholesterol Education Program. Linear regression and logistic regression analyses were performed to assess associations of depressive symptoms with MetS and its components. The incidence of MetS among the participants with depressive symptoms at baseline was 15.27% (20/131). The association of the presence of depressive symptoms with MetS was significant (odds ratio [OR] = 2.53, 95% confidence intervals [CI] = 1.07, 5.95). There was a negative association between depressive symptoms and hypertension (OR = 0.04, 95% CI = 0.002, 0.98). The change in mean arterial pressure varies approximately 1.03 mmHg with a 1-point change in PHQ-9 score. In this study, baseline depressive symptoms were associated with subsequent MetS. The presence of depressive symptoms was negatively associated with elevated mean arterial pressure.
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spelling pubmed-82952972021-07-22 Depressive symptoms and 5-year incident metabolic syndrome among older adults Wu, Qian Hua, Yi-Ying Ma, Qing-Hua Xu, Yong Chen, Xing Pan, Chen-Wei Sci Rep Article Little is known regarding the association between depressive symptoms and metabolic syndrome (MetS) among older Chinese adults. This study aimed to examine the association of depressive symptoms with MetS and its components among Chinese elderly. Based on whether they showed depressive symptoms at baseline, 262 age-gender-matched participants from a community-based cohort study were included. The presence of depressive symptoms was measured using the nine-item Patient Health Questionnaire (PHQ-9). MetS was defined according to the Adult Treatment Panel III of the National Cholesterol Education Program. Linear regression and logistic regression analyses were performed to assess associations of depressive symptoms with MetS and its components. The incidence of MetS among the participants with depressive symptoms at baseline was 15.27% (20/131). The association of the presence of depressive symptoms with MetS was significant (odds ratio [OR] = 2.53, 95% confidence intervals [CI] = 1.07, 5.95). There was a negative association between depressive symptoms and hypertension (OR = 0.04, 95% CI = 0.002, 0.98). The change in mean arterial pressure varies approximately 1.03 mmHg with a 1-point change in PHQ-9 score. In this study, baseline depressive symptoms were associated with subsequent MetS. The presence of depressive symptoms was negatively associated with elevated mean arterial pressure. Nature Publishing Group UK 2021-07-21 /pmc/articles/PMC8295297/ /pubmed/34290362 http://dx.doi.org/10.1038/s41598-021-94503-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Wu, Qian
Hua, Yi-Ying
Ma, Qing-Hua
Xu, Yong
Chen, Xing
Pan, Chen-Wei
Depressive symptoms and 5-year incident metabolic syndrome among older adults
title Depressive symptoms and 5-year incident metabolic syndrome among older adults
title_full Depressive symptoms and 5-year incident metabolic syndrome among older adults
title_fullStr Depressive symptoms and 5-year incident metabolic syndrome among older adults
title_full_unstemmed Depressive symptoms and 5-year incident metabolic syndrome among older adults
title_short Depressive symptoms and 5-year incident metabolic syndrome among older adults
title_sort depressive symptoms and 5-year incident metabolic syndrome among older adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295297/
https://www.ncbi.nlm.nih.gov/pubmed/34290362
http://dx.doi.org/10.1038/s41598-021-94503-y
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