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Drug-associated cues and drug dosage contribute to increased opioid seeking after abstinence

Patients with opioid use disorder experience high rates of relapse during recovery, despite successful completion of rehabilitation programs. A key factor contributing to this problem is the long-lasting nature of drug-seeking behavior associated with opioid use. We modeled this behavior in a rat dr...

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Detalles Bibliográficos
Autores principales: Zanda, Mary Tresa, Floris, Gabriele, Sillivan, Stephanie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295307/
https://www.ncbi.nlm.nih.gov/pubmed/34290298
http://dx.doi.org/10.1038/s41598-021-94214-4

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