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IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer

Breast cancer bone metastasis is currently incurable, ~75% of patients with late-stage breast cancer develop disease recurrence in bone and available treatments are only palliative. We have previously shown that production of the pro-inflammatory cytokine interleukin-1B (IL-1B) by breast cancer cell...

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Detalles Bibliográficos
Autores principales:	Tulotta, Claudia, Lefley, Diane V., Moore, Charlotte K., Amariutei, Ana E., Spicer-Hadlington, Amy R., Quayle, Lewis A., Hughes, Russell O., Ahmed, Khawla, Cookson, Victoria, Evans, Catherine A., Vadakekolathu, Jayakumar, Heath, Paul, Francis, Sheila, Pinteaux, Emmanuel, Pockley, A. Graham, Ottewell, Penelope D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295314/ https://www.ncbi.nlm.nih.gov/pubmed/34290237 http://dx.doi.org/10.1038/s41523-021-00305-w

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