PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer

High-grade serous ovarian cancers (HGSOC) represent the most common subtype of ovarian malignancies. Due to the frequency of late-stage diagnosis and high rates of recurrence following standard of care treatments, novel therapies are needed to promote durable responses. We investigated the anti-tumo...

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Detalles Bibliográficos
Autores principales: Lee, Emily, Szvetecz, Sarah, Polli, Ryan, Grauel, Angelo, Chen, Jayson, Judge, Joyce, Jaiswal, Smita, Maeda, Rie, Schwartz, Stephanie, Voedisch, Bernd, Piksa, Mateusz, Japutra, Chietara, Sadhasivam, Lingheswar, Wang, Yiqin, Carrion, Ana, Isim, Sinan, Liang, Jinsheng, Nicholson, Thomas, Lei, Hong, Fang, Qing, Steinkrauss, Michelle, Walker, Dana, Wagner, Joel, Cremasco, Viviana, Wang, Hui Qin, Galli, Giorgio G., Granda, Brian, Mansfield, Keith, Simmons, Quincey, Nguyen, Andrew Anh, Vincent Jordan, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295318/
https://www.ncbi.nlm.nih.gov/pubmed/34290299
http://dx.doi.org/10.1038/s41598-021-93992-1

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