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Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma

While next-generation sequencing (NGS) is used to guide therapy in patients with metastatic lung adenocarcinoma (LUAD), use of NGS to determine pathologic LN metastasis prior to surgery has not been assessed. To bridge this knowledge gap, we performed NGS using MSK-IMPACT in 426 treatment-naive pati...

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Detalles Bibliográficos
Autores principales: Caso, Raul, Connolly, James G., Zhou, Jian, Tan, Kay See, Choi, James J., Jones, Gregory D., Mastrogiacomo, Brooke, Sanchez-Vega, Francisco, Nguyen, Bastien, Rocco, Gaetano, Molena, Daniela, Sihag, Smita, Adusumilli, Prasad S., Bott, Matthew J., Jones, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295366/
https://www.ncbi.nlm.nih.gov/pubmed/34290393
http://dx.doi.org/10.1038/s41698-021-00210-2