Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma

Glioblastoma (GBM), the most malignant tumor of the central nervous system, is marked by its dynamic response to microenvironmental niches. In particular, this cellular plasticity contributes to the development of an immediate resistance during tumor treatment. Novel insights into the developmental...

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Detalles Bibliográficos
Autores principales: Maier, Julian P., Ravi, Vidhya M., Kueckelhaus, Jan, Behringer, Simon P., Garrelfs, Niklas, Will, Paulina, Sun, Na, von Ehr, Jasmin, Goeldner, Jonathan M., Pfeifer, Dietmar, Follo, Marie, Hannibal, Luciana, Walch, Axel Karl, Hofmann, Ulrich G., Beck, Jürgen, Heiland, Dieter Henrik, Schnell, Oliver, Joseph, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295384/
https://www.ncbi.nlm.nih.gov/pubmed/34290229
http://dx.doi.org/10.1038/s41419-021-03937-9

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