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A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder
Primary erythrocytosis (PE) is a rare myeloproliferative neoplasm in cats resulting in the overproduction of erythrocytes. Current treatment modalities include repeated phlebotomy and chemotherapeutic drugs. These treatments may not be well tolerated by the cat and can present safety and financial c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295705/ https://www.ncbi.nlm.nih.gov/pubmed/34110655 http://dx.doi.org/10.1111/jvim.16194 |
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author | Vasilatis, Demitria M. McGill, Jennifer E. Gilor, Chen |
author_facet | Vasilatis, Demitria M. McGill, Jennifer E. Gilor, Chen |
author_sort | Vasilatis, Demitria M. |
collection | PubMed |
description | Primary erythrocytosis (PE) is a rare myeloproliferative neoplasm in cats resulting in the overproduction of erythrocytes. Current treatment modalities include repeated phlebotomy and chemotherapeutic drugs. These treatments may not be well tolerated by the cat and can present safety and financial challenges to owners. Because of the rarity of PE, prospective studies for new treatment options are difficult to perform. This case report describes the novel use of onion powder in an attempt to produce Heinz body‐induced erythrocyte destruction in order to decrease total erythrocyte mass and normalize the hematocrit in a cat with PE. To our knowledge, the use of onion powder in the treatment of PE in cats has never been described before and may have potential as a safe, low‐cost, and highly accessible alternative treatment for this rare disease. |
format | Online Article Text |
id | pubmed-8295705 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82957052021-07-27 A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder Vasilatis, Demitria M. McGill, Jennifer E. Gilor, Chen J Vet Intern Med SMALL ANIMAL Primary erythrocytosis (PE) is a rare myeloproliferative neoplasm in cats resulting in the overproduction of erythrocytes. Current treatment modalities include repeated phlebotomy and chemotherapeutic drugs. These treatments may not be well tolerated by the cat and can present safety and financial challenges to owners. Because of the rarity of PE, prospective studies for new treatment options are difficult to perform. This case report describes the novel use of onion powder in an attempt to produce Heinz body‐induced erythrocyte destruction in order to decrease total erythrocyte mass and normalize the hematocrit in a cat with PE. To our knowledge, the use of onion powder in the treatment of PE in cats has never been described before and may have potential as a safe, low‐cost, and highly accessible alternative treatment for this rare disease. John Wiley & Sons, Inc. 2021-06-10 2021 /pmc/articles/PMC8295705/ /pubmed/34110655 http://dx.doi.org/10.1111/jvim.16194 Text en © 2021 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | SMALL ANIMAL Vasilatis, Demitria M. McGill, Jennifer E. Gilor, Chen A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder |
title | A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder |
title_full | A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder |
title_fullStr | A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder |
title_full_unstemmed | A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder |
title_short | A novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: Onion powder |
title_sort | novel bone marrow‐sparing treatment for primary erythrocytosis in a cat: onion powder |
topic | SMALL ANIMAL |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295705/ https://www.ncbi.nlm.nih.gov/pubmed/34110655 http://dx.doi.org/10.1111/jvim.16194 |
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