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Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification
RAS is a founding member of the RAS superfamily of GTPases. These small 21 kDa proteins function as molecular switches to initialize signaling cascades involved in various cellular processes, including gene expression, cell growth, and differentiation. RAS is activated by GTP loading and deactivated...
Autores principales: | Osaka, Natsuki, Hirota, Yoshihisa, Ito, Doshun, Ikeda, Yoshiki, Kamata, Ryo, Fujii, Yuki, Chirasani, Venkat R., Campbell, Sharon L., Takeuchi, Koh, Senda, Toshiya, Sasaki, Atsuo T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295990/ https://www.ncbi.nlm.nih.gov/pubmed/34307463 http://dx.doi.org/10.3389/fmolb.2021.707439 |
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