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Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017

Background: The present study aimed to investigate the incidence and characteristics of retinoblastoma in the overall population of Poland. Methods: The retrospective survey of both National Health Fund (NHF) and National Cancer Registry (NCR) databases were performed to identify all retinoblastoma...

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Autores principales: Nowak, Michał S., Romanowska-Dixon, Bożena, Grabska-Liberek, Iwona, Żurek, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296438/
https://www.ncbi.nlm.nih.gov/pubmed/34204493
http://dx.doi.org/10.3390/ijerph18126539
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author Nowak, Michał S.
Romanowska-Dixon, Bożena
Grabska-Liberek, Iwona
Żurek, Michał
author_facet Nowak, Michał S.
Romanowska-Dixon, Bożena
Grabska-Liberek, Iwona
Żurek, Michał
author_sort Nowak, Michał S.
collection PubMed
description Background: The present study aimed to investigate the incidence and characteristics of retinoblastoma in the overall population of Poland. Methods: The retrospective survey of both National Health Fund (NHF) and National Cancer Registry (NCR) databases were performed to identify all retinoblastoma cases in Poland in the years 2010–2017. Results: During 2010–2017, the mean age-standardised incidence of retinoblastoma (the unit of incidence is per 1,000,000 person-years) was 10.15 (95% CI 7.23–13.08) among children aged 0 to 4 years and 5.39 (95% CI 4.18–6.60) in those aged 0 to 9 years. During 2010–2014 (to allow 5 years of follow-up), the mean incidence of retinoblastoma by birth cohort analysis in Poland was 4.89 (95% CI 4.04–5.74) per 100,000 live births, corresponding to an incidence of 1 per 20,561 (95% CI 15,855–25,267) live births. In Poland, 14.6% of children with retinoblastoma had enucleation of the eye globe, 76.8% received different types of chemotherapy combined with focal treatment, 5.9% were treated with external beam radiotherapy, and 2.7% were treated with focal treatments only. Conclusions: The incidence of retinoblastoma and the pattern of medical management of retinoblastoma in Poland was similar to that reported in developed countries in Western Europe, Asia, and North America.
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spelling pubmed-82964382021-07-23 Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017 Nowak, Michał S. Romanowska-Dixon, Bożena Grabska-Liberek, Iwona Żurek, Michał Int J Environ Res Public Health Article Background: The present study aimed to investigate the incidence and characteristics of retinoblastoma in the overall population of Poland. Methods: The retrospective survey of both National Health Fund (NHF) and National Cancer Registry (NCR) databases were performed to identify all retinoblastoma cases in Poland in the years 2010–2017. Results: During 2010–2017, the mean age-standardised incidence of retinoblastoma (the unit of incidence is per 1,000,000 person-years) was 10.15 (95% CI 7.23–13.08) among children aged 0 to 4 years and 5.39 (95% CI 4.18–6.60) in those aged 0 to 9 years. During 2010–2014 (to allow 5 years of follow-up), the mean incidence of retinoblastoma by birth cohort analysis in Poland was 4.89 (95% CI 4.04–5.74) per 100,000 live births, corresponding to an incidence of 1 per 20,561 (95% CI 15,855–25,267) live births. In Poland, 14.6% of children with retinoblastoma had enucleation of the eye globe, 76.8% received different types of chemotherapy combined with focal treatment, 5.9% were treated with external beam radiotherapy, and 2.7% were treated with focal treatments only. Conclusions: The incidence of retinoblastoma and the pattern of medical management of retinoblastoma in Poland was similar to that reported in developed countries in Western Europe, Asia, and North America. MDPI 2021-06-17 /pmc/articles/PMC8296438/ /pubmed/34204493 http://dx.doi.org/10.3390/ijerph18126539 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nowak, Michał S.
Romanowska-Dixon, Bożena
Grabska-Liberek, Iwona
Żurek, Michał
Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017
title Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017
title_full Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017
title_fullStr Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017
title_full_unstemmed Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017
title_short Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017
title_sort incidence and characteristics of retinoblastoma in poland: the first nationwide study 2010–2017
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296438/
https://www.ncbi.nlm.nih.gov/pubmed/34204493
http://dx.doi.org/10.3390/ijerph18126539
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