Synthesis and Biological Evaluation of Fingolimod Derivatives as Antibacterial Agents

[Image: see text] We recently identified fingolimod as a potent antibiofilm compound by screening FDA-approved drugs. To study if the antibacterial activity of fingolimod could be further improved and to explore in-depth structure–activity relationships, we synthesized 28 novel fingolimod derivative...

Descripción completa

Detalles Bibliográficos
Autores principales: Zore, Matej, Gilbert-Girard, Shella, Reigada, Inés, Patel, Jayendra Z., Savijoki, Kirsi, Fallarero, Adyary, Yli-Kauhaluoma, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296573/
https://www.ncbi.nlm.nih.gov/pubmed/34308078
http://dx.doi.org/10.1021/acsomega.1c02591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296573/
https://www.ncbi.nlm.nih.gov/pubmed/34308078
http://dx.doi.org/10.1021/acsomega.1c02591

Ejemplares similares