Cargando…
High-Throughput Virtual Screening for a New Class of Antagonist Targeting LasR of Pseudomonas aeruginosa
[Image: see text] Pseudomonas aeruginosa, an opportunistic human pathogen, causes fatal effects in patients with cystic fibrosis and immunocompromised individuals and leads to around 1000 deaths annually. The quorum sensing mechanism of P. aeruginosa plays a major role in promoting biofilm formation...
Autores principales: | Vetrivel, Aishwarya, Natchimuthu, Santhi, Subramanian, Vidyalakshmi, Murugesan, Rajeswari |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296597/ https://www.ncbi.nlm.nih.gov/pubmed/34308062 http://dx.doi.org/10.1021/acsomega.1c02191 |
Ejemplares similares
-
Pharmacophore and Virtual Screening of JAK3 inhibitors
por: Rajeswari, Murugesan, et al.
Publicado: (2014) -
Virtual Screening of FDA-Approved Drugs against LasR of Pseudomonas aeruginosa for Antibiofilm Potential
por: Sadiq, Suhaib, et al.
Publicado: (2020) -
Characterization of lasR-deficient clinical isolates of Pseudomonas aeruginosa
por: Wang, Yao, et al.
Publicado: (2018) -
Isolation of the Autoinducer-Quenching Strain that Inhibits LasR in Pseudomonas aeruginosa
por: Weng, Lixing, et al.
Publicado: (2014) -
Reversible Signal Binding by the Pseudomonas aeruginosa Quorum-Sensing Signal Receptor LasR
por: Sappington, Kaia J., et al.
Publicado: (2011)