RNA sequencing identifies global transcriptional changes in peripheral CD4(+) cells during active oesophagitis and following epicutaneous immunotherapy in eosinophilic oesophagitis

OBJECTIVE: There are no disease‐modifying therapies for the treatment of eosinophilic oesophagitis (EoE), which is driven by non‐IgE‐mediated allergic inflammation. A recent clinical trial of milk epicutaneous immunotherapy (EPIT) has shown initial promise, with 47% of treated EoE patients toleratin...

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Detalles Bibliográficos
Autores principales: Ruffner, Melanie A, Zhang, Zhe, Maurer, Kelly, Muir, Amanda B, Cianferoni, Antonella, Sullivan, Kathleen E, Spergel, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296633/
https://www.ncbi.nlm.nih.gov/pubmed/34322233
http://dx.doi.org/10.1002/cti2.1314

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