Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products

Humans are unconsciously exposed to environmental toxins including heavy metals as well as various pesticides, which have deleterious effects on human health. Accumulating studies pointed out that exposure to environmental toxins was associated with various cardiopathologic effects. This review summ...

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Detalles Bibliográficos
Autores principales: Yang, Yuanying, Wei, Shanshan, Zhang, Bikui, Li, Wenqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296636/
https://www.ncbi.nlm.nih.gov/pubmed/34305607
http://dx.doi.org/10.3389/fphar.2021.699193
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author Yang, Yuanying
Wei, Shanshan
Zhang, Bikui
Li, Wenqun
author_facet Yang, Yuanying
Wei, Shanshan
Zhang, Bikui
Li, Wenqun
author_sort Yang, Yuanying
collection PubMed
description Humans are unconsciously exposed to environmental toxins including heavy metals as well as various pesticides, which have deleterious effects on human health. Accumulating studies pointed out that exposure to environmental toxins was associated with various cardiopathologic effects. This review summarizes the main mechanisms of cardiotoxicity induced by environmental toxins (cadmium, arsenic and pesticides) and discusses the potential preventive effects of natural products. These findings will provide a theoretical basis and novel agents for the prevention and treatment of environmental toxins-induced cardiotoxicity. Furthermore, the limitations of current studies, future needs and priorities are discussed.
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spelling pubmed-82966362021-07-23 Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products Yang, Yuanying Wei, Shanshan Zhang, Bikui Li, Wenqun Front Pharmacol Pharmacology Humans are unconsciously exposed to environmental toxins including heavy metals as well as various pesticides, which have deleterious effects on human health. Accumulating studies pointed out that exposure to environmental toxins was associated with various cardiopathologic effects. This review summarizes the main mechanisms of cardiotoxicity induced by environmental toxins (cadmium, arsenic and pesticides) and discusses the potential preventive effects of natural products. These findings will provide a theoretical basis and novel agents for the prevention and treatment of environmental toxins-induced cardiotoxicity. Furthermore, the limitations of current studies, future needs and priorities are discussed. Frontiers Media S.A. 2021-07-08 /pmc/articles/PMC8296636/ /pubmed/34305607 http://dx.doi.org/10.3389/fphar.2021.699193 Text en Copyright © 2021 Yang, Wei, Zhang and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Yang, Yuanying
Wei, Shanshan
Zhang, Bikui
Li, Wenqun
Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_full Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_fullStr Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_full_unstemmed Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_short Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_sort recent progress in environmental toxins-induced cardiotoxicity and protective potential of natural products
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296636/
https://www.ncbi.nlm.nih.gov/pubmed/34305607
http://dx.doi.org/10.3389/fphar.2021.699193
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