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Molecular Insights of Nickel Binding to Therapeutic Antibodies as a Possible New Antibody Superantigen
The binding of nickel by immune proteins can manifest as Type IV contact dermatitis (Ni-specific T cells mediated) and less frequently as Type I hypersensitivity with both mechanisms remaining unknown to date. Since there are reports of patients co-manifesting the two hypersensitivities, a common me...
Autores principales: | Su, Chinh Tran-To, Lua, Wai-Heng, Poh, Jun-Jie, Ling, Wei-Li, Yeo, Joshua Yi, Gan, Samuel Ken-En |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296638/ https://www.ncbi.nlm.nih.gov/pubmed/34305906 http://dx.doi.org/10.3389/fimmu.2021.676048 |
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