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Molecular Insights of Nickel Binding to Therapeutic Antibodies as a Possible New Antibody Superantigen

The binding of nickel by immune proteins can manifest as Type IV contact dermatitis (Ni-specific T cells mediated) and less frequently as Type I hypersensitivity with both mechanisms remaining unknown to date. Since there are reports of patients co-manifesting the two hypersensitivities, a common me...

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Detalles Bibliográficos
Autores principales:	Su, Chinh Tran-To, Lua, Wai-Heng, Poh, Jun-Jie, Ling, Wei-Li, Yeo, Joshua Yi, Gan, Samuel Ken-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296638/ https://www.ncbi.nlm.nih.gov/pubmed/34305906 http://dx.doi.org/10.3389/fimmu.2021.676048

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