Cargando…
Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis
Angiostrongylus costaricensis is a zoonotic parasitic nematode described for the first time in 1971 by Pedro Morera and Rodolfo Céspedes in Costa Rica. This parasite causes an infection known as abdominal angiostrongyliasis, affecting mainly school-aged children and young adults. Infection with A. c...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296644/ https://www.ncbi.nlm.nih.gov/pubmed/34294132 http://dx.doi.org/10.1186/s13071-021-04875-3 |
_version_ | 1783725685422948352 |
---|---|
author | Rojas, Alicia Maldonado-Junior, Arnaldo Mora, Javier Morassutti, Alessandra Rodriguez, Rubens Solano-Barquero, Alberto Tijerino, Anamariela Vargas, Marianela Graeff-Teixeira, Carlos |
author_facet | Rojas, Alicia Maldonado-Junior, Arnaldo Mora, Javier Morassutti, Alessandra Rodriguez, Rubens Solano-Barquero, Alberto Tijerino, Anamariela Vargas, Marianela Graeff-Teixeira, Carlos |
author_sort | Rojas, Alicia |
collection | PubMed |
description | Angiostrongylus costaricensis is a zoonotic parasitic nematode described for the first time in 1971 by Pedro Morera and Rodolfo Céspedes in Costa Rica. This parasite causes an infection known as abdominal angiostrongyliasis, affecting mainly school-aged children and young adults. Infection with A. costaricensis has been associated with a myriad of rodent and mollusk species in the Americas and the Caribbean, as its natural hosts and reservoirs. In this commemorative review, we highlight the extensive research collected through a 50-year journey, which includes ecological, pathological, and molecular studies on A. costaricensis and its implicated disease. We also identify major knowledge gaps in its evolutionary history, the ecological role of imported and invasive mollusk species, and immune response. We propose that the advent of -omics analyses will allow us to gather novel information regarding A. costaricensis biology and infection dynamics, as well as to promote the design of much-needed sensitive and specific diagnostic tools. [Image: see text] |
format | Online Article Text |
id | pubmed-8296644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-82966442021-07-22 Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis Rojas, Alicia Maldonado-Junior, Arnaldo Mora, Javier Morassutti, Alessandra Rodriguez, Rubens Solano-Barquero, Alberto Tijerino, Anamariela Vargas, Marianela Graeff-Teixeira, Carlos Parasit Vectors Review Angiostrongylus costaricensis is a zoonotic parasitic nematode described for the first time in 1971 by Pedro Morera and Rodolfo Céspedes in Costa Rica. This parasite causes an infection known as abdominal angiostrongyliasis, affecting mainly school-aged children and young adults. Infection with A. costaricensis has been associated with a myriad of rodent and mollusk species in the Americas and the Caribbean, as its natural hosts and reservoirs. In this commemorative review, we highlight the extensive research collected through a 50-year journey, which includes ecological, pathological, and molecular studies on A. costaricensis and its implicated disease. We also identify major knowledge gaps in its evolutionary history, the ecological role of imported and invasive mollusk species, and immune response. We propose that the advent of -omics analyses will allow us to gather novel information regarding A. costaricensis biology and infection dynamics, as well as to promote the design of much-needed sensitive and specific diagnostic tools. [Image: see text] BioMed Central 2021-07-22 /pmc/articles/PMC8296644/ /pubmed/34294132 http://dx.doi.org/10.1186/s13071-021-04875-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Rojas, Alicia Maldonado-Junior, Arnaldo Mora, Javier Morassutti, Alessandra Rodriguez, Rubens Solano-Barquero, Alberto Tijerino, Anamariela Vargas, Marianela Graeff-Teixeira, Carlos Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis |
title | Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis |
title_full | Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis |
title_fullStr | Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis |
title_full_unstemmed | Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis |
title_short | Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis |
title_sort | abdominal angiostrongyliasis in the americas: fifty years since the discovery of a new metastrongylid species, angiostrongylus costaricensis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296644/ https://www.ncbi.nlm.nih.gov/pubmed/34294132 http://dx.doi.org/10.1186/s13071-021-04875-3 |
work_keys_str_mv | AT rojasalicia abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT maldonadojuniorarnaldo abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT morajavier abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT morassuttialessandra abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT rodriguezrubens abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT solanobarqueroalberto abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT tijerinoanamariela abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT vargasmarianela abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis AT graeffteixeiracarlos abdominalangiostrongyliasisintheamericasfiftyyearssincethediscoveryofanewmetastrongylidspeciesangiostrongyluscostaricensis |