Cargando…
The tRNA-derived fragment 5026a inhibits the proliferation of gastric cancer cells by regulating the PTEN/PI3K/AKT signaling pathway
BACKGROUND: Recently, tRNA-derived fragments (tRFs) have been shown to serve important biological functions. However, the role of tRFs in gastric cancer has not been fully elucidated. This study aimed to identify the tumor suppressor role of tRF-5026a (tRF-18-79MP9P04) in gastric cancer. METHODS: Qu...
Autores principales: | Zhu, Linwen, Li, Zhe, Yu, Xiuchong, Ruan, Yao, Shen, Yijing, Shao, Yongfu, Zhang, Xinjun, Ye, Guoliang, Guo, Junming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296675/ https://www.ncbi.nlm.nih.gov/pubmed/34294122 http://dx.doi.org/10.1186/s13287-021-02497-1 |
Ejemplares similares
-
Absolute quantification of a plasma tRNA-derived fragment for the diagnosis and prognosis of gastric cancer
por: Zhang, Shuangshuang, et al.
Publicado: (2023) -
tRNA derived fragments:A novel player in gene regulation and applications in cancer
por: Zhang, Shuangshuang, et al.
Publicado: (2023) -
Extracellular vesicles-associated tRNA-derived fragments (tRFs): biogenesis, biological functions, and their role as potential biomarkers in human diseases
por: Weng, Qiuyan, et al.
Publicado: (2022) -
Global profile of tRNA-derived small RNAs in gastric cancer patient plasma and identification of tRF-33-P4R8YP9LON4VDP as a new tumor suppressor
por: Shen, Yijing, et al.
Publicado: (2021) -
Action mechanisms and research methods of tRNA-derived small RNAs
por: Xie, Yaoyao, et al.
Publicado: (2020)