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The tRNA-derived fragment 5026a inhibits the proliferation of gastric cancer cells by regulating the PTEN/PI3K/AKT signaling pathway

BACKGROUND: Recently, tRNA-derived fragments (tRFs) have been shown to serve important biological functions. However, the role of tRFs in gastric cancer has not been fully elucidated. This study aimed to identify the tumor suppressor role of tRF-5026a (tRF-18-79MP9P04) in gastric cancer. METHODS: Qu...

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Detalles Bibliográficos
Autores principales: Zhu, Linwen, Li, Zhe, Yu, Xiuchong, Ruan, Yao, Shen, Yijing, Shao, Yongfu, Zhang, Xinjun, Ye, Guoliang, Guo, Junming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296675/
https://www.ncbi.nlm.nih.gov/pubmed/34294122
http://dx.doi.org/10.1186/s13287-021-02497-1

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