Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression

BACKGROUND: Prostate cancer is caused by genomic aberrations in normal epithelial cells, however clinical translation of findings from analyses of cancer cells alone has been very limited. A deeper understanding of the tumour microenvironment is needed to identify the key drivers of disease progress...

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Detalles Bibliográficos
Autores principales: Mangiola, Stefano, McCoy, Patrick, Modrak, Martin, Souza-Fonseca-Guimaraes, Fernando, Blashki, Daniel, Stuchbery, Ryan, Keam, Simon P., Kerger, Michael, Chow, Ken, Nasa, Chayanica, Le Page, Melanie, Lister, Natalie, Monard, Simon, Peters, Justin, Dundee, Phil, Williams, Scott G., Costello, Anthony J., Neeson, Paul J., Pal, Bhupinder, Huntington, Nicholas D., Corcoran, Niall M., Papenfuss, Anthony T., Hovens, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296706/
https://www.ncbi.nlm.nih.gov/pubmed/34294073
http://dx.doi.org/10.1186/s12885-021-08529-6

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