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PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is characterized by a tumor-like expansion of the synovium and subsequent destruction of adjacent articular cartilage and bone. In our previous work we showed that phosphatase and tension homolog deleted on chromosome 10 (PTEN) contributes to the activation of fibroblast-li...
Autores principales: | Li, Xiao-Feng, Wu, Sha, Yan, Qi, Wu, Yuan-Yuan, Chen, He, Yin, Su-Qin, Chen, Xin, Wang, Hua, Li, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296842/ https://www.ncbi.nlm.nih.gov/pubmed/34305608 http://dx.doi.org/10.3389/fphar.2021.700373 |
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