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In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs)

To cope with the shortage of filtering facepiece respirators (FFRs) caused by the coronavirus disease (COVID-19), healthcare institutions have been forced to reuse FFRs using different decontamination methods, including vapor hydrogen peroxide (VHP). However, most healthcare institutions still strug...

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Autores principales: Al-Hadyan, Khaled, Alsbeih, Ghazi, Nobah, Ahmad, Lindstrom, Jeffrey, Falatah, Sawsan, Faran, Nawarh, Al-Ghamdi, Salem, Moftah, Belal, Alhmaid, Rashed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297238/
https://www.ncbi.nlm.nih.gov/pubmed/34281105
http://dx.doi.org/10.3390/ijerph18137169
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author Al-Hadyan, Khaled
Alsbeih, Ghazi
Nobah, Ahmad
Lindstrom, Jeffrey
Falatah, Sawsan
Faran, Nawarh
Al-Ghamdi, Salem
Moftah, Belal
Alhmaid, Rashed
author_facet Al-Hadyan, Khaled
Alsbeih, Ghazi
Nobah, Ahmad
Lindstrom, Jeffrey
Falatah, Sawsan
Faran, Nawarh
Al-Ghamdi, Salem
Moftah, Belal
Alhmaid, Rashed
author_sort Al-Hadyan, Khaled
collection PubMed
description To cope with the shortage of filtering facepiece respirators (FFRs) caused by the coronavirus disease (COVID-19), healthcare institutions have been forced to reuse FFRs using different decontamination methods, including vapor hydrogen peroxide (VHP). However, most healthcare institutions still struggle with evaluating the effect of VHP on filtration efficiency (FE) of the decontaminated FFRs. We developed a low-cost in-house FE assessment using a novel 3D-printed air duct. Furthermore, we assessed the FE of seven types of FFRs. Following 10 VHP cycles, we evaluated the FE of KN95 and 3M-N95 masks. The 3M-N95 and Benehal-N95 masks showed significant lower FE (80.4–91.8%) at fine particle sizes (0.3–1 µm) compared to other FFRs (FE ≥ 98.1%, p < 0.05). Following 10 VHP cycles, the FE of KN95 masks was almost stable (FE stability > 99.1%) for all particle sizes, while 3M-N95 masks were stable only at 2 and 5 µm (FE stability > 98.0%). Statistically, FE stability of 3M-N95 masks at 0.3, 0.5, and 0.7 µm was significantly lower (p ≤ 0.006) than 2 and 5 µm. The in-house FE assessment may be used as an emergency procedure to validate the decontaminated FFRs, as well as a screening option for production control of FFRs. Following VHP cycles, both masks showed high stability at 5 µm, the size of the most suspected droplets implicated in COVID-19 transmission.
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spelling pubmed-82972382021-07-23 In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs) Al-Hadyan, Khaled Alsbeih, Ghazi Nobah, Ahmad Lindstrom, Jeffrey Falatah, Sawsan Faran, Nawarh Al-Ghamdi, Salem Moftah, Belal Alhmaid, Rashed Int J Environ Res Public Health Article To cope with the shortage of filtering facepiece respirators (FFRs) caused by the coronavirus disease (COVID-19), healthcare institutions have been forced to reuse FFRs using different decontamination methods, including vapor hydrogen peroxide (VHP). However, most healthcare institutions still struggle with evaluating the effect of VHP on filtration efficiency (FE) of the decontaminated FFRs. We developed a low-cost in-house FE assessment using a novel 3D-printed air duct. Furthermore, we assessed the FE of seven types of FFRs. Following 10 VHP cycles, we evaluated the FE of KN95 and 3M-N95 masks. The 3M-N95 and Benehal-N95 masks showed significant lower FE (80.4–91.8%) at fine particle sizes (0.3–1 µm) compared to other FFRs (FE ≥ 98.1%, p < 0.05). Following 10 VHP cycles, the FE of KN95 masks was almost stable (FE stability > 99.1%) for all particle sizes, while 3M-N95 masks were stable only at 2 and 5 µm (FE stability > 98.0%). Statistically, FE stability of 3M-N95 masks at 0.3, 0.5, and 0.7 µm was significantly lower (p ≤ 0.006) than 2 and 5 µm. The in-house FE assessment may be used as an emergency procedure to validate the decontaminated FFRs, as well as a screening option for production control of FFRs. Following VHP cycles, both masks showed high stability at 5 µm, the size of the most suspected droplets implicated in COVID-19 transmission. MDPI 2021-07-04 /pmc/articles/PMC8297238/ /pubmed/34281105 http://dx.doi.org/10.3390/ijerph18137169 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al-Hadyan, Khaled
Alsbeih, Ghazi
Nobah, Ahmad
Lindstrom, Jeffrey
Falatah, Sawsan
Faran, Nawarh
Al-Ghamdi, Salem
Moftah, Belal
Alhmaid, Rashed
In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs)
title In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs)
title_full In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs)
title_fullStr In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs)
title_full_unstemmed In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs)
title_short In-House Filtration Efficiency Assessment of Vapor Hydrogen Peroxide Decontaminated Filtering Facepiece Respirators (FFRs)
title_sort in-house filtration efficiency assessment of vapor hydrogen peroxide decontaminated filtering facepiece respirators (ffrs)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297238/
https://www.ncbi.nlm.nih.gov/pubmed/34281105
http://dx.doi.org/10.3390/ijerph18137169
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