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Model‐guided development of an evolutionarily stable yeast chassis

First‐principle metabolic modelling holds potential for designing microbial chassis that are resilient against phenotype reversal due to adaptive mutations. Yet, the theory of model‐based chassis design has rarely been put to rigorous experimental test. Here, we report the development of Saccharomyc...

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Detalles Bibliográficos
Autores principales: Pereira, Filipa, Lopes, Helder, Maia, Paulo, Meyer, Britta, Nocon, Justyna, Jouhten, Paula, Konstantinidis, Dimitrios, Kafkia, Eleni, Rocha, Miguel, Kötter, Peter, Rocha, Isabel, Patil, Kiran R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297383/
https://www.ncbi.nlm.nih.gov/pubmed/34292675
http://dx.doi.org/10.15252/msb.202110253