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Model‐guided development of an evolutionarily stable yeast chassis
First‐principle metabolic modelling holds potential for designing microbial chassis that are resilient against phenotype reversal due to adaptive mutations. Yet, the theory of model‐based chassis design has rarely been put to rigorous experimental test. Here, we report the development of Saccharomyc...
Autores principales: | Pereira, Filipa, Lopes, Helder, Maia, Paulo, Meyer, Britta, Nocon, Justyna, Jouhten, Paula, Konstantinidis, Dimitrios, Kafkia, Eleni, Rocha, Miguel, Kötter, Peter, Rocha, Isabel, Patil, Kiran R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297383/ https://www.ncbi.nlm.nih.gov/pubmed/34292675 http://dx.doi.org/10.15252/msb.202110253 |
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