Trifluoromethyl-substituted 3,5-bis(arylidene)-4-piperidones as potential anti-hepatoma and anti-inflammation agents by inhibiting NF-кB activation

Some methoxy-, hydroxyl-, pyridyl-, or fluoro-substituted 3,5-bis(arylidene)-4-piperidones (BAPs) could reduce inflammation and promote hepatoma cell apoptosis by inhibiting activation of NF-κB, especially after introduction of trifluoromethyl. Herein, a series of trifluoromethyl-substituted BAPs (4...

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Detalles Bibliográficos
Autores principales: Cong, Wei, Sun, Yue, Sun, Yi-Fan, Yan, Wei-Bin, Zhang, Yu-Long, Gao, Zhong-Fei, Wang, Chun-Hua, Hou, Gui-Ge, Zhang, Jia-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297402/
https://www.ncbi.nlm.nih.gov/pubmed/34284695
http://dx.doi.org/10.1080/14756366.2021.1953996

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