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Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells
Pyroptosis is a form of programmed cell death, in which gasdermin E (GSDME) plays an important role in cancer cells, which can be induced by activated caspase-3 on apoptotic stimulation. Triclabendazole is a new type of imidazole in fluke resistance and has been approved by the FDA for the treatment...
Autores principales: | Yan, Liang, Liu, Yi, Ma, Xue-feng, Hou, Dan, Zhang, Yu-hui, Sun, Yong, Shi, Shan-shan, Forouzanfar, Tim, Lin, Hai-yan, Fan, Jun, Wu, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297466/ https://www.ncbi.nlm.nih.gov/pubmed/34305590 http://dx.doi.org/10.3389/fphar.2021.670081 |
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