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Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size

PURPOSE: The aim of this study was to evaluate mammographic findings associated with invasive lobular carcinoma in different age groups, taking into account breast composition and tumour size. MATERIAL AND METHODS: A total of 1023 invasive lobular carcinoma preoperative mammograms were evaluated. Ac...

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Autores principales: Tagliati, Corrado, Cerimele, Federico, Di Martino, Antonietta, Capone, Fabrizio, Di Matteo, Marialuisa, Caputo, Nevia, Pressanti, Gabriella Lucidi, Mingliang, Ying, Baldassarre, Silvia, Giovagnoni, Andrea, Giuseppetti, Gian Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297481/
https://www.ncbi.nlm.nih.gov/pubmed/34322184
http://dx.doi.org/10.5114/pjr.2021.107426
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author Tagliati, Corrado
Cerimele, Federico
Di Martino, Antonietta
Capone, Fabrizio
Di Matteo, Marialuisa
Caputo, Nevia
Pressanti, Gabriella Lucidi
Mingliang, Ying
Baldassarre, Silvia
Giovagnoni, Andrea
Giuseppetti, Gian Marco
author_facet Tagliati, Corrado
Cerimele, Federico
Di Martino, Antonietta
Capone, Fabrizio
Di Matteo, Marialuisa
Caputo, Nevia
Pressanti, Gabriella Lucidi
Mingliang, Ying
Baldassarre, Silvia
Giovagnoni, Andrea
Giuseppetti, Gian Marco
author_sort Tagliati, Corrado
collection PubMed
description PURPOSE: The aim of this study was to evaluate mammographic findings associated with invasive lobular carcinoma in different age groups, taking into account breast composition and tumour size. MATERIAL AND METHODS: A total of 1023 invasive lobular carcinoma preoperative mammograms were evaluated. According to the American College of Radiology Breast Imaging Reporting and Data System, cancer mammographic findings were classified as mass, calcifications, architectural distortion, and asymmetry, and breasts were assessed as dense (C or D breast composition) or non-dense (A or B). The patient cohort was subdivided into 3 age groups (< 50, 50-69, ≥ 70 years of age). In order to make the size and age groups dichotomous variables and to perform multiple regression analysis, a cut-off of 10 mm was chosen for tumour size, and < 50-years-old and 50-69-years-old age groups were grouped together (< 70-years-old age group). RESULTS: Significant results of multivariate analysis were the association between mass finding and non-dense breasts and size ≥ 10 mm (p < 0.0001), between calcifications, and dense breasts, size < 10 mm and < 70-years-old age group (p < 0.0001), between distortion and < 70-years-old age group (p = 0.0366), and between asymmetry and ≥ 70-years-old age group (p = 0.0090). CONCLUSIONS: Various mammographic findings are differently associated with age group, breast composition, and tumour size.
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spelling pubmed-82974812021-07-27 Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size Tagliati, Corrado Cerimele, Federico Di Martino, Antonietta Capone, Fabrizio Di Matteo, Marialuisa Caputo, Nevia Pressanti, Gabriella Lucidi Mingliang, Ying Baldassarre, Silvia Giovagnoni, Andrea Giuseppetti, Gian Marco Pol J Radiol Original Paper PURPOSE: The aim of this study was to evaluate mammographic findings associated with invasive lobular carcinoma in different age groups, taking into account breast composition and tumour size. MATERIAL AND METHODS: A total of 1023 invasive lobular carcinoma preoperative mammograms were evaluated. According to the American College of Radiology Breast Imaging Reporting and Data System, cancer mammographic findings were classified as mass, calcifications, architectural distortion, and asymmetry, and breasts were assessed as dense (C or D breast composition) or non-dense (A or B). The patient cohort was subdivided into 3 age groups (< 50, 50-69, ≥ 70 years of age). In order to make the size and age groups dichotomous variables and to perform multiple regression analysis, a cut-off of 10 mm was chosen for tumour size, and < 50-years-old and 50-69-years-old age groups were grouped together (< 70-years-old age group). RESULTS: Significant results of multivariate analysis were the association between mass finding and non-dense breasts and size ≥ 10 mm (p < 0.0001), between calcifications, and dense breasts, size < 10 mm and < 70-years-old age group (p < 0.0001), between distortion and < 70-years-old age group (p = 0.0366), and between asymmetry and ≥ 70-years-old age group (p = 0.0090). CONCLUSIONS: Various mammographic findings are differently associated with age group, breast composition, and tumour size. Termedia Publishing House 2021-06-11 /pmc/articles/PMC8297481/ /pubmed/34322184 http://dx.doi.org/10.5114/pjr.2021.107426 Text en Copyright © Polish Medical Society of Radiology 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0). License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Paper
Tagliati, Corrado
Cerimele, Federico
Di Martino, Antonietta
Capone, Fabrizio
Di Matteo, Marialuisa
Caputo, Nevia
Pressanti, Gabriella Lucidi
Mingliang, Ying
Baldassarre, Silvia
Giovagnoni, Andrea
Giuseppetti, Gian Marco
Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
title Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
title_full Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
title_fullStr Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
title_full_unstemmed Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
title_short Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
title_sort invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297481/
https://www.ncbi.nlm.nih.gov/pubmed/34322184
http://dx.doi.org/10.5114/pjr.2021.107426
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