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Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
PURPOSE: The aim of this study was to evaluate mammographic findings associated with invasive lobular carcinoma in different age groups, taking into account breast composition and tumour size. MATERIAL AND METHODS: A total of 1023 invasive lobular carcinoma preoperative mammograms were evaluated. Ac...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297481/ https://www.ncbi.nlm.nih.gov/pubmed/34322184 http://dx.doi.org/10.5114/pjr.2021.107426 |
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author | Tagliati, Corrado Cerimele, Federico Di Martino, Antonietta Capone, Fabrizio Di Matteo, Marialuisa Caputo, Nevia Pressanti, Gabriella Lucidi Mingliang, Ying Baldassarre, Silvia Giovagnoni, Andrea Giuseppetti, Gian Marco |
author_facet | Tagliati, Corrado Cerimele, Federico Di Martino, Antonietta Capone, Fabrizio Di Matteo, Marialuisa Caputo, Nevia Pressanti, Gabriella Lucidi Mingliang, Ying Baldassarre, Silvia Giovagnoni, Andrea Giuseppetti, Gian Marco |
author_sort | Tagliati, Corrado |
collection | PubMed |
description | PURPOSE: The aim of this study was to evaluate mammographic findings associated with invasive lobular carcinoma in different age groups, taking into account breast composition and tumour size. MATERIAL AND METHODS: A total of 1023 invasive lobular carcinoma preoperative mammograms were evaluated. According to the American College of Radiology Breast Imaging Reporting and Data System, cancer mammographic findings were classified as mass, calcifications, architectural distortion, and asymmetry, and breasts were assessed as dense (C or D breast composition) or non-dense (A or B). The patient cohort was subdivided into 3 age groups (< 50, 50-69, ≥ 70 years of age). In order to make the size and age groups dichotomous variables and to perform multiple regression analysis, a cut-off of 10 mm was chosen for tumour size, and < 50-years-old and 50-69-years-old age groups were grouped together (< 70-years-old age group). RESULTS: Significant results of multivariate analysis were the association between mass finding and non-dense breasts and size ≥ 10 mm (p < 0.0001), between calcifications, and dense breasts, size < 10 mm and < 70-years-old age group (p < 0.0001), between distortion and < 70-years-old age group (p = 0.0366), and between asymmetry and ≥ 70-years-old age group (p = 0.0090). CONCLUSIONS: Various mammographic findings are differently associated with age group, breast composition, and tumour size. |
format | Online Article Text |
id | pubmed-8297481 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-82974812021-07-27 Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size Tagliati, Corrado Cerimele, Federico Di Martino, Antonietta Capone, Fabrizio Di Matteo, Marialuisa Caputo, Nevia Pressanti, Gabriella Lucidi Mingliang, Ying Baldassarre, Silvia Giovagnoni, Andrea Giuseppetti, Gian Marco Pol J Radiol Original Paper PURPOSE: The aim of this study was to evaluate mammographic findings associated with invasive lobular carcinoma in different age groups, taking into account breast composition and tumour size. MATERIAL AND METHODS: A total of 1023 invasive lobular carcinoma preoperative mammograms were evaluated. According to the American College of Radiology Breast Imaging Reporting and Data System, cancer mammographic findings were classified as mass, calcifications, architectural distortion, and asymmetry, and breasts were assessed as dense (C or D breast composition) or non-dense (A or B). The patient cohort was subdivided into 3 age groups (< 50, 50-69, ≥ 70 years of age). In order to make the size and age groups dichotomous variables and to perform multiple regression analysis, a cut-off of 10 mm was chosen for tumour size, and < 50-years-old and 50-69-years-old age groups were grouped together (< 70-years-old age group). RESULTS: Significant results of multivariate analysis were the association between mass finding and non-dense breasts and size ≥ 10 mm (p < 0.0001), between calcifications, and dense breasts, size < 10 mm and < 70-years-old age group (p < 0.0001), between distortion and < 70-years-old age group (p = 0.0366), and between asymmetry and ≥ 70-years-old age group (p = 0.0090). CONCLUSIONS: Various mammographic findings are differently associated with age group, breast composition, and tumour size. Termedia Publishing House 2021-06-11 /pmc/articles/PMC8297481/ /pubmed/34322184 http://dx.doi.org/10.5114/pjr.2021.107426 Text en Copyright © Polish Medical Society of Radiology 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0). License (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Original Paper Tagliati, Corrado Cerimele, Federico Di Martino, Antonietta Capone, Fabrizio Di Matteo, Marialuisa Caputo, Nevia Pressanti, Gabriella Lucidi Mingliang, Ying Baldassarre, Silvia Giovagnoni, Andrea Giuseppetti, Gian Marco Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size |
title | Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size |
title_full | Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size |
title_fullStr | Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size |
title_full_unstemmed | Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size |
title_short | Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size |
title_sort | invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297481/ https://www.ncbi.nlm.nih.gov/pubmed/34322184 http://dx.doi.org/10.5114/pjr.2021.107426 |
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