Cargando…

Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease

Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is an idiopathic condition related to a dysregulated immune response to commensal intestinal microflora in a genetically susceptible host. As a global disease, the morbidity of IBD reached a rate of 84...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Guihua, Shen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297505/
https://www.ncbi.nlm.nih.gov/pubmed/34307315
http://dx.doi.org/10.3389/fbioe.2021.635764
_version_ 1783725875698597888
author Chen, Guihua
Shen, Jun
author_facet Chen, Guihua
Shen, Jun
author_sort Chen, Guihua
collection PubMed
description Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is an idiopathic condition related to a dysregulated immune response to commensal intestinal microflora in a genetically susceptible host. As a global disease, the morbidity of IBD reached a rate of 84.3 per 100,000 persons and reflected a continued gradual upward trajectory. The medical cost of IBD is also notably extremely high. For example, in Europe, it has €3,500 in CD and €2,000 in UC per patient per year, respectively. In addition, taking into account the work productivity loss and the reduced quality of life, the indirect costs are incalculable. In modern times, the diagnosis of IBD is still a subjective judgment based on laboratory tests and medical images. Its early diagnosis and intervention is therefore a challenging goal and also the key to control its progression. Artificial intelligence (AI)-assisted diagnosis and prognosis prediction has proven effective in many fields including gastroenterology. In this study, support vector machines were utilized to distinguish the significant features in IBD. As a result, the reliability of IBD diagnosis due to its impressive performance in classifying and addressing region problems was improved. Convolutional neural networks are advanced image processing algorithms that are currently in existence. Digestive endoscopic images can therefore be better understood by automatically detecting and classifying lesions. This study aims to summarize AI application in the area of IBD, objectively evaluate the performance of these methods, and ultimately understand the algorithm–dataset combination in the studies.
format Online
Article
Text
id pubmed-8297505
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-82975052021-07-23 Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease Chen, Guihua Shen, Jun Front Bioeng Biotechnol Bioengineering and Biotechnology Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is an idiopathic condition related to a dysregulated immune response to commensal intestinal microflora in a genetically susceptible host. As a global disease, the morbidity of IBD reached a rate of 84.3 per 100,000 persons and reflected a continued gradual upward trajectory. The medical cost of IBD is also notably extremely high. For example, in Europe, it has €3,500 in CD and €2,000 in UC per patient per year, respectively. In addition, taking into account the work productivity loss and the reduced quality of life, the indirect costs are incalculable. In modern times, the diagnosis of IBD is still a subjective judgment based on laboratory tests and medical images. Its early diagnosis and intervention is therefore a challenging goal and also the key to control its progression. Artificial intelligence (AI)-assisted diagnosis and prognosis prediction has proven effective in many fields including gastroenterology. In this study, support vector machines were utilized to distinguish the significant features in IBD. As a result, the reliability of IBD diagnosis due to its impressive performance in classifying and addressing region problems was improved. Convolutional neural networks are advanced image processing algorithms that are currently in existence. Digestive endoscopic images can therefore be better understood by automatically detecting and classifying lesions. This study aims to summarize AI application in the area of IBD, objectively evaluate the performance of these methods, and ultimately understand the algorithm–dataset combination in the studies. Frontiers Media S.A. 2021-07-08 /pmc/articles/PMC8297505/ /pubmed/34307315 http://dx.doi.org/10.3389/fbioe.2021.635764 Text en Copyright © 2021 Chen and Shen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Chen, Guihua
Shen, Jun
Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease
title Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease
title_full Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease
title_fullStr Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease
title_full_unstemmed Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease
title_short Artificial Intelligence Enhances Studies on Inflammatory Bowel Disease
title_sort artificial intelligence enhances studies on inflammatory bowel disease
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297505/
https://www.ncbi.nlm.nih.gov/pubmed/34307315
http://dx.doi.org/10.3389/fbioe.2021.635764
work_keys_str_mv AT chenguihua artificialintelligenceenhancesstudiesoninflammatoryboweldisease
AT shenjun artificialintelligenceenhancesstudiesoninflammatoryboweldisease