Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality

We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of...

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Autores principales: Soria, Jaime, Chiappe, Alfredo, Gallardo, Jorge, Zunt, Joseph R, Lescano, Andres G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297700/
https://www.ncbi.nlm.nih.gov/pubmed/34307735
http://dx.doi.org/10.1093/ofid/ofab345
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author Soria, Jaime
Chiappe, Alfredo
Gallardo, Jorge
Zunt, Joseph R
Lescano, Andres G
author_facet Soria, Jaime
Chiappe, Alfredo
Gallardo, Jorge
Zunt, Joseph R
Lescano, Andres G
author_sort Soria, Jaime
collection PubMed
description We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.
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spelling pubmed-82977002021-07-23 Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality Soria, Jaime Chiappe, Alfredo Gallardo, Jorge Zunt, Joseph R Lescano, Andres G Open Forum Infect Dis Brief Reports We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission. Oxford University Press 2021-06-30 /pmc/articles/PMC8297700/ /pubmed/34307735 http://dx.doi.org/10.1093/ofid/ofab345 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Soria, Jaime
Chiappe, Alfredo
Gallardo, Jorge
Zunt, Joseph R
Lescano, Andres G
Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality
title Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality
title_full Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality
title_fullStr Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality
title_full_unstemmed Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality
title_short Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality
title_sort tuberculous meningitis: impact of timing of treatment initiation on mortality
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297700/
https://www.ncbi.nlm.nih.gov/pubmed/34307735
http://dx.doi.org/10.1093/ofid/ofab345
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AT zuntjosephr tuberculousmeningitisimpactoftimingoftreatmentinitiationonmortality
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