Fission yeast Rad8/HLTF facilitates Rad52-dependent chromosomal rearrangements through PCNA lysine 107 ubiquitination

Gross chromosomal rearrangements (GCRs), including translocation, deletion, and inversion, can cause cell death and genetic diseases such as cancer in multicellular organisms. Rad51, a DNA strand exchange protein, suppresses GCRs by repairing spontaneous DNA damage through a conservative way of homo...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Jie, Xu, Ran, Mongia, Piyusha, Toyofuku, Naoko, Nakagawa, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297803/
https://www.ncbi.nlm.nih.gov/pubmed/34292936
http://dx.doi.org/10.1371/journal.pgen.1009671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297803/
https://www.ncbi.nlm.nih.gov/pubmed/34292936
http://dx.doi.org/10.1371/journal.pgen.1009671

Ejemplares similares