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Microtubules and Gαo-signaling modulate the preferential secretion of young insulin secretory granules in islet β cells via independent pathways

For sustainable function, each pancreatic islet β cell maintains thousands of insulin secretory granules (SGs) at all times. Glucose stimulation induces the secretion of a small portion of these SGs and simultaneously boosts SG biosynthesis to sustain this stock. The failure of these processes, ofte...

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Detalles Bibliográficos
Autores principales:	Hu, Ruiying, Zhu, Xiaodong, Yuan, Mingyang, Ho, Kung-Hsien, Kaverina, Irina, Gu, Guoqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297875/ https://www.ncbi.nlm.nih.gov/pubmed/34292976 http://dx.doi.org/10.1371/journal.pone.0241939

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