Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis

BACKGROUND: The pathogenesis of contact dermatitis, a common inflammatory skin disease with limited treatment options, is held to be driven by inflammasome activation induced by allergens and irritants. We here aim to identify inflammasome‐targeting treatment strategies for irritant contact dermatit...

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Detalles Bibliográficos
Autores principales: Bonnekoh, Hanna, Vera, Carolina, Abad‐Perez, Angela, Radetzki, Silke, Neuenschwander, Martin, Specker, Edgar, Mahnke, Niklas Amadeus, Frischbutter, Stefan, Latz, Eicke, Nazaré, Marc, Kries, Jens v., Maurer, Marcus, Scheffel, Jörg, Krause, Karoline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297992/
https://www.ncbi.nlm.nih.gov/pubmed/34322217
http://dx.doi.org/10.1002/clt2.12045

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