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Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era

Since December 2019, Wuhan, China, has experienced an outbreak of coronavirus disease (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pregnant women are deductively considered to be in immunosuppressive condition for the safety of semi-allograft fetus...

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Detalles Bibliográficos
Autores principales: Lv, Dan, Peng, Jing, Long, Rui, Lin, Xingguang, Wang, Renjie, Wu, Di, He, Mengzhou, Liao, Shujie, Zhao, Yun, Deng, Dongrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298030/
https://www.ncbi.nlm.nih.gov/pubmed/34305916
http://dx.doi.org/10.3389/fimmu.2021.683440
Descripción
Sumario:Since December 2019, Wuhan, China, has experienced an outbreak of coronavirus disease (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pregnant women are deductively considered to be in immunosuppressive condition for the safety of semi-allograft fetuses, which increases the risk of being infected by the virus. In this review, we analyzed the unique immunological characteristics of pregnant women and reviewed their known outcomes at different trimesters from the perspective of underlying mechanisms that have been studied and speculated so far.