Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era

Since December 2019, Wuhan, China, has experienced an outbreak of coronavirus disease (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pregnant women are deductively considered to be in immunosuppressive condition for the safety of semi-allograft fetus...

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Autores principales: Lv, Dan, Peng, Jing, Long, Rui, Lin, Xingguang, Wang, Renjie, Wu, Di, He, Mengzhou, Liao, Shujie, Zhao, Yun, Deng, Dongrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298030/
https://www.ncbi.nlm.nih.gov/pubmed/34305916
http://dx.doi.org/10.3389/fimmu.2021.683440
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author Lv, Dan
Peng, Jing
Long, Rui
Lin, Xingguang
Wang, Renjie
Wu, Di
He, Mengzhou
Liao, Shujie
Zhao, Yun
Deng, Dongrui
author_facet Lv, Dan
Peng, Jing
Long, Rui
Lin, Xingguang
Wang, Renjie
Wu, Di
He, Mengzhou
Liao, Shujie
Zhao, Yun
Deng, Dongrui
author_sort Lv, Dan
collection PubMed
description Since December 2019, Wuhan, China, has experienced an outbreak of coronavirus disease (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pregnant women are deductively considered to be in immunosuppressive condition for the safety of semi-allograft fetuses, which increases the risk of being infected by the virus. In this review, we analyzed the unique immunological characteristics of pregnant women and reviewed their known outcomes at different trimesters from the perspective of underlying mechanisms that have been studied and speculated so far.
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spelling pubmed-82980302021-07-23 Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era Lv, Dan Peng, Jing Long, Rui Lin, Xingguang Wang, Renjie Wu, Di He, Mengzhou Liao, Shujie Zhao, Yun Deng, Dongrui Front Immunol Immunology Since December 2019, Wuhan, China, has experienced an outbreak of coronavirus disease (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pregnant women are deductively considered to be in immunosuppressive condition for the safety of semi-allograft fetuses, which increases the risk of being infected by the virus. In this review, we analyzed the unique immunological characteristics of pregnant women and reviewed their known outcomes at different trimesters from the perspective of underlying mechanisms that have been studied and speculated so far. Frontiers Media S.A. 2021-07-08 /pmc/articles/PMC8298030/ /pubmed/34305916 http://dx.doi.org/10.3389/fimmu.2021.683440 Text en Copyright © 2021 Lv, Peng, Long, Lin, Wang, Wu, He, Liao, Zhao and Deng https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Lv, Dan
Peng, Jing
Long, Rui
Lin, Xingguang
Wang, Renjie
Wu, Di
He, Mengzhou
Liao, Shujie
Zhao, Yun
Deng, Dongrui
Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era
title Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era
title_full Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era
title_fullStr Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era
title_full_unstemmed Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era
title_short Exploring the Immunopathogenesis of Pregnancy With COVID-19 at the Vaccination Era
title_sort exploring the immunopathogenesis of pregnancy with covid-19 at the vaccination era
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298030/
https://www.ncbi.nlm.nih.gov/pubmed/34305916
http://dx.doi.org/10.3389/fimmu.2021.683440
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