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In vitro Assays and Imaging Methods for Drug Discovery for Cardiac Fibrosis
As a result of stress, injury, or aging, cardiac fibrosis is characterized by excessive deposition of extracellular matrix (ECM) components resulting in pathological remodeling, tissue stiffening, ventricular dilatation, and cardiac dysfunction that contribute to heart failure (HF) and eventually de...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298031/ https://www.ncbi.nlm.nih.gov/pubmed/34305651 http://dx.doi.org/10.3389/fphys.2021.697270 |