Aurora A kinase activation: Different means to different ends

Aurora A is a serine/threonine kinase essential for mitotic entry and spindle assembly. Recent molecular studies have revealed the existence of multiple, distinct mechanisms of Aurora A activation, each occurring at specific subcellular locations, optimized for cellular context, and primed by signal...

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Detalles Bibliográficos
Autores principales: Tavernier, Nicolas, Sicheri, Frank, Pintard, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298103/
https://www.ncbi.nlm.nih.gov/pubmed/34287649
http://dx.doi.org/10.1083/jcb.202106128
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author Tavernier, Nicolas
Sicheri, Frank
Pintard, Lionel
author_facet Tavernier, Nicolas
Sicheri, Frank
Pintard, Lionel
author_sort Tavernier, Nicolas
collection PubMed
description Aurora A is a serine/threonine kinase essential for mitotic entry and spindle assembly. Recent molecular studies have revealed the existence of multiple, distinct mechanisms of Aurora A activation, each occurring at specific subcellular locations, optimized for cellular context, and primed by signaling events including phosphorylation and oxidation.
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spelling pubmed-82981032022-03-06 Aurora A kinase activation: Different means to different ends Tavernier, Nicolas Sicheri, Frank Pintard, Lionel J Cell Biol Viewpoint Aurora A is a serine/threonine kinase essential for mitotic entry and spindle assembly. Recent molecular studies have revealed the existence of multiple, distinct mechanisms of Aurora A activation, each occurring at specific subcellular locations, optimized for cellular context, and primed by signaling events including phosphorylation and oxidation. Rockefeller University Press 2021-07-21 /pmc/articles/PMC8298103/ /pubmed/34287649 http://dx.doi.org/10.1083/jcb.202106128 Text en © 2021 Tavernier et al. http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Viewpoint
Tavernier, Nicolas
Sicheri, Frank
Pintard, Lionel
Aurora A kinase activation: Different means to different ends
title Aurora A kinase activation: Different means to different ends
title_full Aurora A kinase activation: Different means to different ends
title_fullStr Aurora A kinase activation: Different means to different ends
title_full_unstemmed Aurora A kinase activation: Different means to different ends
title_short Aurora A kinase activation: Different means to different ends
title_sort aurora a kinase activation: different means to different ends
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298103/
https://www.ncbi.nlm.nih.gov/pubmed/34287649
http://dx.doi.org/10.1083/jcb.202106128
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