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The Evolution of Risk Assessment in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a chronic debilitating disease that carries an unacceptably high morbidity and mortality rate despite improved survival with modern therapies. The combination of several modifiable and nonmodifiable variables yields a robust risk assessment across various ava...

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Detalles Bibliográficos
Autores principales: Murthy, Sandhya, Benza, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Houston Methodist DeBakey Heart & Vascular Center 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298117/
https://www.ncbi.nlm.nih.gov/pubmed/34326933
http://dx.doi.org/10.14797/LRPR7655
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author Murthy, Sandhya
Benza, Raymond
author_facet Murthy, Sandhya
Benza, Raymond
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description Pulmonary arterial hypertension (PAH) is a chronic debilitating disease that carries an unacceptably high morbidity and mortality rate despite improved survival with modern therapies. The combination of several modifiable and nonmodifiable variables yields a robust risk assessment across various available clinical calculators. The role of risk calculation is integral to managing PAH and aids in the timely referral to expert centers and potentially lung transplantation. Studies are ongoing to determine the role of risk calculators in the framework of clinical trials and to elucidate novel markers of high risk in PAH.
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spelling pubmed-82981172021-07-28 The Evolution of Risk Assessment in Pulmonary Arterial Hypertension Murthy, Sandhya Benza, Raymond Methodist Debakey Cardiovasc J Review Article Pulmonary arterial hypertension (PAH) is a chronic debilitating disease that carries an unacceptably high morbidity and mortality rate despite improved survival with modern therapies. The combination of several modifiable and nonmodifiable variables yields a robust risk assessment across various available clinical calculators. The role of risk calculation is integral to managing PAH and aids in the timely referral to expert centers and potentially lung transplantation. Studies are ongoing to determine the role of risk calculators in the framework of clinical trials and to elucidate novel markers of high risk in PAH. Houston Methodist DeBakey Heart & Vascular Center 2021-07-01 /pmc/articles/PMC8298117/ /pubmed/34326933 http://dx.doi.org/10.14797/LRPR7655 Text en Copyright: © 2021 The Author(s) https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC-BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any noncommercial medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Review Article
Murthy, Sandhya
Benza, Raymond
The Evolution of Risk Assessment in Pulmonary Arterial Hypertension
title The Evolution of Risk Assessment in Pulmonary Arterial Hypertension
title_full The Evolution of Risk Assessment in Pulmonary Arterial Hypertension
title_fullStr The Evolution of Risk Assessment in Pulmonary Arterial Hypertension
title_full_unstemmed The Evolution of Risk Assessment in Pulmonary Arterial Hypertension
title_short The Evolution of Risk Assessment in Pulmonary Arterial Hypertension
title_sort evolution of risk assessment in pulmonary arterial hypertension
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298117/
https://www.ncbi.nlm.nih.gov/pubmed/34326933
http://dx.doi.org/10.14797/LRPR7655
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