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Overexpression of TOLLIP Protects against Acute Kidney Injury after Paraquat Intoxication through Inhibiting NLRP3 Inflammasome Activation Modulated by Toll-Like Receptor 2/4 Signaling

Paraquat (PQ) can cause multiorgan failure including acute kidney injury (AKI). Our prior study showed that Toll-interacting protein (TOLLIP) protected against PQ-induced acute lung injury. However, the role of TOLLIP in PQ-induced AKI remains undefined. This study was aimed at understanding the rol...

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Detalles Bibliográficos
Autores principales:	Zheng, Qiang, Zhao, Hang, Jia, Dong, Han, Xu, Liu, Zhenning, Zhao, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298172/ https://www.ncbi.nlm.nih.gov/pubmed/34335089 http://dx.doi.org/10.1155/2021/5571272

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