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A case with hepatic immune-related adverse events caused by nivolumab exhibiting impaired accumulation of regulatory T cells

Systemic administration of anti-programmed cell death 1 (PD-1) antibody (Ab) has achieved remarkable success in metastatic cancers. The blockade of PD-1-mediated signaling pathways sometimes cause immune-related adverse events (irAEs) due to restored anti-cancer as well as anti-self immunity. Althou...

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Detalles Bibliográficos
Autores principales: Sekai, Ikue, Hagiwara, Satoru, Watanabe, Tomohiro, Kudo, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298218/
https://www.ncbi.nlm.nih.gov/pubmed/33665689
http://dx.doi.org/10.1007/s12328-020-01317-y

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