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Bone morphogenetic protein 2-induced cellular chemotaxis drives tissue patterning during critical-sized bone defect healing: an in silico study

Critical-sized bone defects are critical healing conditions that, if left untreated, often lead to non-unions. To reduce the risk, critical-sized bone defects are often treated with recombinant human BMP-2. Although enhanced bone tissue formation is observed when BMP-2 is administered locally to the...

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Detalles Bibliográficos
Autores principales: Borgiani, Edoardo, Duda, Georg N., Willie, Bettina M., Checa, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298257/
https://www.ncbi.nlm.nih.gov/pubmed/34047890
http://dx.doi.org/10.1007/s10237-021-01466-0