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Bone morphogenetic protein 2-induced cellular chemotaxis drives tissue patterning during critical-sized bone defect healing: an in silico study
Critical-sized bone defects are critical healing conditions that, if left untreated, often lead to non-unions. To reduce the risk, critical-sized bone defects are often treated with recombinant human BMP-2. Although enhanced bone tissue formation is observed when BMP-2 is administered locally to the...
Autores principales: | Borgiani, Edoardo, Duda, Georg N., Willie, Bettina M., Checa, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298257/ https://www.ncbi.nlm.nih.gov/pubmed/34047890 http://dx.doi.org/10.1007/s10237-021-01466-0 |
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