Cargando…
CYP2D6 phenotype explains reported yohimbine concentrations in four severe acute intoxications
The indole alkaloid yohimbine is an alpha-2 receptor antagonist used for its sympathomimetic effects. Several cases of yohimbine intoxication have been reported and the most recent one involved four individuals taking a yohimbine-containing drug powder. All individuals developed severe intoxication...
Autores principales: | Mueller-Schoell, Anna, Michelet, Robin, Weinelt, Ferdinand, Kloft, Charlotte, Mikus, Gerd |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298364/ https://www.ncbi.nlm.nih.gov/pubmed/34027562 http://dx.doi.org/10.1007/s00204-021-03082-4 |
Ejemplares similares
-
Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies
por: Mueller-Schoell, Anna, et al.
Publicado: (2021) -
Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups
por: Mueller-Schoell, Anna, et al.
Publicado: (2021) -
Microdialysis of Voriconazole and its N-Oxide Metabolite: Amalgamating Knowledge of Distribution and Metabolism Processes in Humans
por: Schulz, Josefine, et al.
Publicado: (2022) -
Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide
por: Schulz, Josefine, et al.
Publicado: (2022) -
Oral Yohimbine as a New Probe Drug to Predict CYP2D6 Activity: Results of a Fixed-Sequence Phase I Trial
por: Vay, Manuela, et al.
Publicado: (2020)