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Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3

CRISPR-Cas12j is a recently identified family of miniaturized RNA-guided endonucleases from phages. These ribonucleoproteins provide a compact scaffold gathering all key activities of a genome editing tool. We provide the first structural insight into the Cas12j family by determining the cryoEM stru...

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Detalles Bibliográficos
Autores principales:	Carabias, Arturo, Fuglsang, Anders, Temperini, Piero, Pape, Tillmann, Sofos, Nicholas, Stella, Stefano, Erlendsson, Simon, Montoya, Guillermo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298400/ https://www.ncbi.nlm.nih.gov/pubmed/34294706 http://dx.doi.org/10.1038/s41467-021-24707-3

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