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Diagnostic potential of serum extracellular vesicles expressing prostate-specific membrane antigen in urologic malignancies

We aimed to develop a sandwich ELISA to detect prostate-specific membrane antigen (PSMA) on small extracellular vesicles (EVs) using T-cell immunoglobulin domain and mucin domain-containing protein 4 (Tim4) as a capture molecule for EVs and to evaluate its diagnostic potential in urologic malignanci...

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Detalles Bibliográficos
Autores principales: Kawakami, Kyojiro, Fujita, Yasunori, Kato, Taku, Horie, Kengo, Koie, Takuya, Umezawa, Keitaro, Tsumoto, Hiroki, Miura, Yuri, Katagiri, Yasuo, Miyazaki, Tatsuhiko, Ohsawa, Ikuroh, Mizutani, Kosuke, Ito, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298409/
https://www.ncbi.nlm.nih.gov/pubmed/34294841
http://dx.doi.org/10.1038/s41598-021-94603-9