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Clinically applicable artificial intelligence system for dental diagnosis with CBCT

In this study, a novel AI system based on deep learning methods was evaluated to determine its real-time performance of CBCT imaging diagnosis of anatomical landmarks, pathologies, clinical effectiveness, and safety when used by dentists in a clinical setting. The system consists of 5 modules: ROI-l...

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Autores principales: Ezhov, Matvey, Gusarev, Maxim, Golitsyna, Maria, Yates, Julian M., Kushnerev, Evgeny, Tamimi, Dania, Aksoy, Secil, Shumilov, Eugene, Sanders, Alex, Orhan, Kaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298426/
https://www.ncbi.nlm.nih.gov/pubmed/34294759
http://dx.doi.org/10.1038/s41598-021-94093-9
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author Ezhov, Matvey
Gusarev, Maxim
Golitsyna, Maria
Yates, Julian M.
Kushnerev, Evgeny
Tamimi, Dania
Aksoy, Secil
Shumilov, Eugene
Sanders, Alex
Orhan, Kaan
author_facet Ezhov, Matvey
Gusarev, Maxim
Golitsyna, Maria
Yates, Julian M.
Kushnerev, Evgeny
Tamimi, Dania
Aksoy, Secil
Shumilov, Eugene
Sanders, Alex
Orhan, Kaan
author_sort Ezhov, Matvey
collection PubMed
description In this study, a novel AI system based on deep learning methods was evaluated to determine its real-time performance of CBCT imaging diagnosis of anatomical landmarks, pathologies, clinical effectiveness, and safety when used by dentists in a clinical setting. The system consists of 5 modules: ROI-localization-module (segmentation of teeth and jaws), tooth-localization and numeration-module, periodontitis-module, caries-localization-module, and periapical-lesion-localization-module. These modules use CNN based on state-of-the-art architectures. In total, 1346 CBCT scans were used to train the modules. After annotation and model development, the AI system was tested for diagnostic capabilities of the Diagnocat AI system. 24 dentists participated in the clinical evaluation of the system. 30 CBCT scans were examined by two groups of dentists, where one group was aided by Diagnocat and the other was unaided. The results for the overall sensitivity and specificity for aided and unaided groups were calculated as an aggregate of all conditions. The sensitivity values for aided and unaided groups were 0.8537 and 0.7672 while specificity was 0.9672 and 0.9616 respectively. There was a statistically significant difference between the groups (p = 0.032). This study showed that the proposed AI system significantly improved the diagnostic capabilities of dentists.
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spelling pubmed-82984262021-07-23 Clinically applicable artificial intelligence system for dental diagnosis with CBCT Ezhov, Matvey Gusarev, Maxim Golitsyna, Maria Yates, Julian M. Kushnerev, Evgeny Tamimi, Dania Aksoy, Secil Shumilov, Eugene Sanders, Alex Orhan, Kaan Sci Rep Article In this study, a novel AI system based on deep learning methods was evaluated to determine its real-time performance of CBCT imaging diagnosis of anatomical landmarks, pathologies, clinical effectiveness, and safety when used by dentists in a clinical setting. The system consists of 5 modules: ROI-localization-module (segmentation of teeth and jaws), tooth-localization and numeration-module, periodontitis-module, caries-localization-module, and periapical-lesion-localization-module. These modules use CNN based on state-of-the-art architectures. In total, 1346 CBCT scans were used to train the modules. After annotation and model development, the AI system was tested for diagnostic capabilities of the Diagnocat AI system. 24 dentists participated in the clinical evaluation of the system. 30 CBCT scans were examined by two groups of dentists, where one group was aided by Diagnocat and the other was unaided. The results for the overall sensitivity and specificity for aided and unaided groups were calculated as an aggregate of all conditions. The sensitivity values for aided and unaided groups were 0.8537 and 0.7672 while specificity was 0.9672 and 0.9616 respectively. There was a statistically significant difference between the groups (p = 0.032). This study showed that the proposed AI system significantly improved the diagnostic capabilities of dentists. Nature Publishing Group UK 2021-07-22 /pmc/articles/PMC8298426/ /pubmed/34294759 http://dx.doi.org/10.1038/s41598-021-94093-9 Text en © The Author(s) 2021, corrected publication 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ezhov, Matvey
Gusarev, Maxim
Golitsyna, Maria
Yates, Julian M.
Kushnerev, Evgeny
Tamimi, Dania
Aksoy, Secil
Shumilov, Eugene
Sanders, Alex
Orhan, Kaan
Clinically applicable artificial intelligence system for dental diagnosis with CBCT
title Clinically applicable artificial intelligence system for dental diagnosis with CBCT
title_full Clinically applicable artificial intelligence system for dental diagnosis with CBCT
title_fullStr Clinically applicable artificial intelligence system for dental diagnosis with CBCT
title_full_unstemmed Clinically applicable artificial intelligence system for dental diagnosis with CBCT
title_short Clinically applicable artificial intelligence system for dental diagnosis with CBCT
title_sort clinically applicable artificial intelligence system for dental diagnosis with cbct
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298426/
https://www.ncbi.nlm.nih.gov/pubmed/34294759
http://dx.doi.org/10.1038/s41598-021-94093-9
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