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Transcriptional-regulatory convergence across functional MDD risk variants identified by massively parallel reporter assays
Family and population studies indicate clear heritability of major depressive disorder (MDD), though its underlying biology remains unclear. The majority of single-nucleotide polymorphism (SNP) linkage blocks associated with MDD by genome-wide association studies (GWASes) are believed to alter trans...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298436/ https://www.ncbi.nlm.nih.gov/pubmed/34294677 http://dx.doi.org/10.1038/s41398-021-01493-6 |