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Transcriptional-regulatory convergence across functional MDD risk variants identified by massively parallel reporter assays

Family and population studies indicate clear heritability of major depressive disorder (MDD), though its underlying biology remains unclear. The majority of single-nucleotide polymorphism (SNP) linkage blocks associated with MDD by genome-wide association studies (GWASes) are believed to alter trans...

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Detalles Bibliográficos
Autores principales: Mulvey, Bernard, Dougherty, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298436/
https://www.ncbi.nlm.nih.gov/pubmed/34294677
http://dx.doi.org/10.1038/s41398-021-01493-6