A single dose of replication-competent VSV-vectored vaccine expressing SARS-CoV-2 S1 protects against virus replication in a hamster model of severe COVID-19

The development of effective countermeasures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the COVID-19 pandemic, is a priority. We designed and produced ConVac, a replication-competent vesicular stomatitis virus (VSV) vaccine vector that expresses t...

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Detalles Bibliográficos
Autores principales: Malherbe, Delphine C., Kurup, Drishya, Wirblich, Christoph, Ronk, Adam J., Mire, Chad, Kuzmina, Natalia, Shaik, Noor, Periasamy, Sivakumar, Hyde, Matthew A., Williams, Julie M., Shi, Pei-Yong, Schnell, Matthias J., Bukreyev, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298481/
https://www.ncbi.nlm.nih.gov/pubmed/34294728
http://dx.doi.org/10.1038/s41541-021-00352-1

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