Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production

The cellular identity of pancreatic polypeptide (Ppy)-expressing γ-cells, one of the rarest pancreatic islet cell-type, remains elusive. Within islets, glucagon and somatostatin, released respectively from α- and δ-cells, modulate the secretion of insulin by β-cells. Dysregulation of insulin product...

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Detalles Bibliográficos
Autores principales: Perez-Frances, Marta, van Gurp, Léon, Abate, Maria Valentina, Cigliola, Valentina, Furuyama, Kenichiro, Bru-Tari, Eva, Oropeza, Daniel, Carreaux, Taïna, Fujitani, Yoshio, Thorel, Fabrizio, Herrera, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298494/
https://www.ncbi.nlm.nih.gov/pubmed/34294685
http://dx.doi.org/10.1038/s41467-021-24788-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298494/
https://www.ncbi.nlm.nih.gov/pubmed/34294685
http://dx.doi.org/10.1038/s41467-021-24788-0

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