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Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis

The role of cis-elements and their aberrations remains unclear in esophageal squamous cell carcinoma (ESCC, further abbreviated EC). Here we survey 28 H3K27ac-marked active enhancer profiles and 50 transcriptomes in primary EC, metastatic lymph node cancer (LNC), and adjacent normal (Nor) esophageal...

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Detalles Bibliográficos
Autores principales:	Ye, Bo, Fan, Dandan, Xiong, Weiwei, Li, Min, Yuan, Jian, Jiang, Qi, Zhao, Yuting, Lin, Jianxiang, Liu, Jie, Lv, Yilv, Wang, Xiongjun, Li, Zhigang, Su, Jianzhong, Qiao, Yunbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298514/ https://www.ncbi.nlm.nih.gov/pubmed/34294701 http://dx.doi.org/10.1038/s41467-021-24813-2

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