Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect

A 46-year-old man developed chronic thromboembolic pulmonary hypertension and atrial fibrillation after acute pulmonary embolism. He was found incidentally to have an isolated secundum atrial septal defect, as well as a homozygous mutation for the plasminogen activator inhibitor-1 gene. He was succe...

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Autores principales: Kilinc, Mehmet, Yaylali, Yalin Tolga, Yildizeli, Bedrettin, Tas, Serpil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298561/
https://www.ncbi.nlm.nih.gov/pubmed/34317315
http://dx.doi.org/10.1016/j.jaccas.2020.01.016
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author Kilinc, Mehmet
Yaylali, Yalin Tolga
Yildizeli, Bedrettin
Tas, Serpil
author_facet Kilinc, Mehmet
Yaylali, Yalin Tolga
Yildizeli, Bedrettin
Tas, Serpil
author_sort Kilinc, Mehmet
collection PubMed
description A 46-year-old man developed chronic thromboembolic pulmonary hypertension and atrial fibrillation after acute pulmonary embolism. He was found incidentally to have an isolated secundum atrial septal defect, as well as a homozygous mutation for the plasminogen activator inhibitor-1 gene. He was successfully treated with pulmonary endarterectomy and atrial septal defect repair. He has continued to do well on a regimen of dabigatran. (Level of Difficulty: Beginner.)
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spelling pubmed-82985612021-07-26 Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect Kilinc, Mehmet Yaylali, Yalin Tolga Yildizeli, Bedrettin Tas, Serpil JACC Case Rep Case Report A 46-year-old man developed chronic thromboembolic pulmonary hypertension and atrial fibrillation after acute pulmonary embolism. He was found incidentally to have an isolated secundum atrial septal defect, as well as a homozygous mutation for the plasminogen activator inhibitor-1 gene. He was successfully treated with pulmonary endarterectomy and atrial septal defect repair. He has continued to do well on a regimen of dabigatran. (Level of Difficulty: Beginner.) Elsevier 2020-03-25 /pmc/articles/PMC8298561/ /pubmed/34317315 http://dx.doi.org/10.1016/j.jaccas.2020.01.016 Text en © 2020 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kilinc, Mehmet
Yaylali, Yalin Tolga
Yildizeli, Bedrettin
Tas, Serpil
Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect
title Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect
title_full Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect
title_fullStr Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect
title_full_unstemmed Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect
title_short Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect
title_sort chronic thromboembolic pulmonary hypertension secondary to thrombophilia and incidentally diagnosed atrial septal defect
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298561/
https://www.ncbi.nlm.nih.gov/pubmed/34317315
http://dx.doi.org/10.1016/j.jaccas.2020.01.016
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