BCG therapy is associated with long-term, durable induction of Treg signature genes by epigenetic modulation

Induction of immunosuppressive T-regulatory cells (Tregs) is a desirable goal in autoimmunity, and perhaps other immune diseases of activation. One promising avenue is with the bacille-calmette-guérin (BCG) vaccine in autoimmune type 1 diabetes (T1D). Its administration is associated with gradual cl...

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Detalles Bibliográficos
Autores principales: Keefe, Ryan C., Takahashi, Hiroyuki, Tran, Lisa, Nelson, Kacie, Ng, Nathan, Kühtreiber, Willem M., Faustman, Denise L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298580/
https://www.ncbi.nlm.nih.gov/pubmed/34294806
http://dx.doi.org/10.1038/s41598-021-94529-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298580/
https://www.ncbi.nlm.nih.gov/pubmed/34294806
http://dx.doi.org/10.1038/s41598-021-94529-2

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